Technology Process of <(fluoro-4 benzoyl)-3 propyl>-1 phenylamino-4 trans-decahydroquinoleine
There total 9 articles about <(fluoro-4 benzoyl)-3 propyl>-1 phenylamino-4 trans-decahydroquinoleine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 72.7 percent / para-toluenesulfonic acid / benzene; hexane / 72 h / Heating
2: 51 percent / bis(methoxy-2 ethoxy)-aluminodihydrure de sodium / toluene / 48 h / 40 °C
3: sodium hydrogencarbonate / butan-1-ol / Heating
4: aq. HCl / 3 h
With
bis(methoxy-2 ethoxy)-aluminodihydrure de sodium; sodium hydrogencarbonate;
toluene-4-sulfonic acid;
In
hydrogenchloride; hexane; toluene; butan-1-ol; benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 72.7 percent / para-toluenesulfonic acid / benzene; hexane / 72 h / Heating
2: 51 percent / bis(methoxy-2 ethoxy)-aluminodihydrure de sodium / toluene / 48 h / 40 °C
3: sodium hydrogencarbonate / butan-1-ol / Heating
4: aq. HCl / 3 h
With
bis(methoxy-2 ethoxy)-aluminodihydrure de sodium; sodium hydrogencarbonate;
toluene-4-sulfonic acid;
In
hydrogenchloride; hexane; toluene; butan-1-ol; benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: aluminium chloride / CH2Cl2 / 18 h / Ambient temperature
2: Amberlite 15 / 20 h / Heating
3: sodium hydrogencarbonate / butan-1-ol / Heating
4: aq. HCl / 3 h
With
aluminium trichloride; Amberlite 15; sodium hydrogencarbonate;
In
hydrogenchloride; dichloromethane; butan-1-ol;