4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

Base Information

Chemical Name:4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide
CAS No.:114847-17-5
Molecular Formula:C₁₆H₁₆N₂O₂S
Molecular Weight:300.381
Hs Code.:

Synonyms:4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

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Chemical Property of 4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

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Technology Process of 4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

There total 3 articles about 4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 114828-51-2
5-(4-methylphenyl)-3-(2-thienylmethylene)-2(3H)-furanone

: 114847-17-5
4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; Ambient temperature;

Reference yield:

: 98-03-3
thiophene-2-carbaldehyde

: 114847-17-5
4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / CH₃COONa / acetic anhydride / Heating

2: 70 percent / hydrazine hydrate / ethanol / Ambient temperature

With sodium acetate; hydrazine hydrate; In ethanol; acetic anhydride;

Reference yield:

: 4619-20-9
3-(4-methylbenzoyl)propionic acid

: 114847-17-5
4-Oxo-2-[1-thiophen-2-yl-meth-(Z)-ylidene]-4-p-tolyl-butyric acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / CH₃COONa / acetic anhydride / Heating

2: 70 percent / hydrazine hydrate / ethanol / Ambient temperature

With sodium acetate; hydrazine hydrate; In ethanol; acetic anhydride;