benzyl alcohol-α,α,hydroxy-d3

Base Information

• Chemical Name: benzyl alcohol-α,α,hydroxy-d3
• CAS No.: 42463-63-8
• Molecular Formula: C₇H₈O
• Molecular Weight: 111.116
• Mol file: 42463-63-8.mol

Synonyms:benzyl alcohol-α,α,hydroxy-d3

Chemical Property of benzyl alcohol-α,α,hydroxy-d3

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl alcohol-α,α,hydroxy-d3

There total 10 articles about benzyl alcohol-α,α,hydroxy-d3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) → benzyl alcohol-α,α,hydroxy-d3 (42463-63-8)

Guidance literature:

benzoic acid methyl ester; With lithium aluminium deuteride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 24h;

With water-d2; In tetrahydrofuran; diethyl ether;

DOI:10.1021/acs.orglett.0c01485

Reference yield:

benzonitrile (100-47-0) → α,O-Dideuteriobenzylalkohol (113297-96-4) + benzyl alcohol-α,α,hydroxy-d3 (42463-63-8) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With formaldehyd; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; In water-d2; toluene; at 90 ℃;

DOI:10.1039/c9cy01484e

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → benzyl alcohol-α,α,hydroxy-d3 (42463-63-8)

Guidance literature:

With [ruthenium(II)(chloride)(2-aminomethyl-6-tolylpyridine)(1,4-bis(diphenylphosphino)butane)]; d8-isopropanol; potassium tert-butylate; at 50 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c1dt10498e

upstream raw materials:

benzyl alcohol

benzoic acid ethyl ester

3-Phenylpropenol

benzoic acid

Downstream raw materials:

1-(1-deuterio-1,3-diphenylprop-2-yn-1-yl)piperidine

Benzaldehyde-d

(E)-3-deuterio-1,3-diphenyl prop-2-en-1-one

3-deuterio-1,3-diphenyl-1-propanone