methyl 2-dodecylbenzoate

Base Information

• Chemical Name: methyl 2-dodecylbenzoate
• CAS No.: 102684-72-0
• Molecular Formula: C₂₀H₃₂O₂
• Molecular Weight: 304.473
• Mol file: 102684-72-0.mol

Synonyms:methyl 2-dodecylbenzoate

Chemical Property of methyl 2-dodecylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-dodecylbenzoate

There total 4 articles about methyl 2-dodecylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-bromobenzoic acid methyl ester (610-94-6) + dodecyl 4-methylbenzenesulphonate (10157-76-3) → methyl 2-dodecylbenzoate (102684-72-0)

Guidance literature:

With [2,2]bipyridinyl; vitamin B₁₂; manganese; chloro-trimethyl-silane; potassium iodide; nickel dibromide; In N,N-dimethyl-formamide; at 30 ℃; for 30h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c7cc01932g

Reference yield: 67.0%

methyl 2-(1-dodecynyl)benzoate (102684-71-9) → methyl 2-dodecylbenzoate (102684-72-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 6h; under 2068.6 Torr;

DOI:10.1021/jm00158a021

Reference yield:

2-bromobenzoic acid methyl ester (610-94-6) → methyl 2-dodecylbenzoate (102684-72-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 21 percent / (Ph₃P)2PdCl₂, CuI, Et₃N / 16 h / Heating

2: 67 percent / H₂ / 10percent Pd/C / ethyl acetate / 6 h / 2068.6 Torr

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; hydrogen; triethylamine; palladium on activated charcoal; In ethyl acetate;

DOI:10.1021/jm00158a021

upstream raw materials:

methyl 2-(1-dodecynyl)benzoate

1-dodecyne

2-bromobenzoic acid methyl ester

dodecyl 4-methylbenzenesulphonate

Downstream raw materials:

5-(2-dodecylphenyl)-5-(3-carboxylpropyl)-δ-valerolactone

Refernces

• 1、 Perchonock,Uzinskas,McCarthy,Erhard,Gleason,Wasserman,Muccitelli,DeVan,Tucker,Vickery. "Synthesis and structure-activity relationship studies of a series of 5-aryl-4,6-dithianonanedioic acids and related compounds: A novel class of leukotriene antagonists". . p. 1442 - 1452. Retrieved 2007/10/02.