Methyl 3-(1-Tritylimidazol-4-yl) Propionate

Base Information

• Chemical Name: Methyl 3-(1-Tritylimidazol-4-yl) Propionate
• CAS No.: 102676-60-8
• Molecular Formula: C26H24 N2 O2
• Molecular Weight: 396.489
• DSSTox Substance ID: DTXSID10440579
• Nikkaji Number: J1.305.535A
• Mol file: 102676-60-8.mol

Synonyms:102676-60-8;Methyl 3-(1-Tritylimidazol-4-yl) Propionate;Methyl 3-(1-tritylimidazol-4-yl)propanoate;methyl 3-(1-trityl-1h-imidazol-4-yl)propanoate;3-(1-Trityl-1H-imidazol-4-yl)-propionic acid methyl ester;Methyl 3-(1-Tritylimidazol-4-yl)Propionate;SCHEMBL1037593;DTXSID10440579;FSUWVSSCCGVYLS-UHFFFAOYSA-N;MFCD04039625;AKOS015969451;AS-31079;CS-0207725;FT-0672295;1-Trityl-imidazole-4-propionic acid methyl ester;1-Trityl-1H-imidazole-4-propionic acid methyl ester;3-(1-trityl-1H-imidazol-4-yl)propanoic acid methyl ester;3-(1-Trityl-1H-imidazol-4-yl)propionic acid methyl ester;Methyl 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoate;methyl 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propionate

Chemical Property of Methyl 3-(1-Tritylimidazol-4-yl) Propionate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 140-142°C
• Refractive Index: 1.591
• Boiling Point: 530.985°C at 760 mmHg
• Flash Point: 274.93°C
• PSA: 44.12000
• Density: 1.1g/cm³
• LogP: 4.82890
• Storage Temp.: -20?C Freezer
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 396.183778013
• Heavy Atom Count: 30
• Complexity: 488

Purity/Quality:

97% ^*data from raw suppliers

Methyl3-(1-Tritylimidazol-4-yl)Propionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)CCC1=CN(C=N1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4
• Uses: Methyl 3-(1-Tritylimidazol-4-yl) Propionate (cas# 102676-60-8) is a compound useful in organic synthesis.

Technology Process of Methyl 3-(1-Tritylimidazol-4-yl) Propionate

There total 14 articles about Methyl 3-(1-Tritylimidazol-4-yl) Propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trans-1-trityl-4-imidazoleacrylic acid methyl ester (138408-36-3) → 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester (102676-60-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 4h;

DOI:10.1016/j.bmc.2005.09.002

Reference yield: 98.0%

trityl chloride (76-83-5) + methyl 3-(4-imidazolyl)propionate (31434-93-2) → 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester (102676-60-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

DOI:10.1021/jm00106a038

Reference yield: 81.0%

trityl chloride (76-83-5) + 3-(1H-imidazol-4-yl)propionic acid methyl ester hydrochloride (53958-94-4) → 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester (102676-60-8)

Guidance literature:

With triethylamine; In acetonitrile; for 12h; Ambient temperature;

DOI:10.1021/jm950476

upstream raw materials:

trityl chloride

methyl 3-(4-imidazolyl)propionate

3-(1H-imidazol-4-yl)propionic acid methyl ester hydrochloride

trans-1-trityl-4-imidazoleacrylic acid methyl ester

Downstream raw materials:

3-(1-trityl-1H-imidazol-4-yl)propan-1-ol

2-Benzyl-3-(1-trityl-1H-imidazol-4-yl)-propionic acid methyl ester

3-(1H-1-triphenylmethylimidazol-4-yl)propanoic acid

N-[3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-3-(1-trityl-1H-imidazol-4-yl)-propionamide