C₂₂H₂₄N₆O₄

Base Information

• Chemical Name: C₂₂H₂₄N₆O₄
• CAS No.: 1541182-85-7
• Molecular Formula: C₂₂H₂₄N₆O₄
• Molecular Weight: 436.47
• Mol file: 1541182-85-7.mol

Synonyms:C₂₂H₂₄N₆O₄

Chemical Property of C₂₂H₂₄N₆O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₂H₂₄N₆O₄

There total 3 articles about C₂₂H₂₄N₆O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C32H40N6O8 (1541182-84-6) → C22H24N6O4 (1541182-85-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ja412729s

Reference yield:

C27H32N6O6 → C22H24N6O4 (1541182-85-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1002/anie.202014670

Reference yield:

2,6-dimethylbenzene-1,4-diamine (7218-02-2) → C22H24N6O4 (1541182-85-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

2.1: dimethyl sulfoxide / 3 h / 20 °C / Inert atmosphere

2.2: 240 h / 80 °C / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

With trifluoroacetic acid; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide;

DOI:10.1021/ja412729s

upstream raw materials:

C₃₂H₄₀N₆O₈

2,6-dimethylbenzene-1,4-diamine

Downstream raw materials:

C₆₄H₆₀N₁₂O₁₆

Refernces

• 1、 Sebaoun, Laure,Maurizot, Victor,Granier, Thierry,Kauffmann, Brice,Huc, Ivan. "Aromatic oligoamide β-sheet foldamers". supporting information. p. 2168 - 2174. Retrieved 2014/03/21.