2-chloro-5-trifluoromethylphenylethylene oxide

Base Information

• Chemical Name: 2-chloro-5-trifluoromethylphenylethylene oxide
• CAS No.: 545410-66-0
• Molecular Formula: C₉H₆ClF₃O
• Molecular Weight: 222.594
• Mol file: 545410-66-0.mol

Synonyms:2-chloro-5-trifluoromethylphenylethylene oxide

Chemical Property of 2-chloro-5-trifluoromethylphenylethylene oxide

Chemical Property:

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Technology Process of 2-chloro-5-trifluoromethylphenylethylene oxide

There total 1 articles about 2-chloro-5-trifluoromethylphenylethylene oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-5-(trifluoromethyl)benzaldehyde (82386-89-8) + trimethylsulphonium iodide (2181-42-2) → 2-chloro-5-trifluoromethylphenylethylene oxide (545410-66-0)

Guidance literature:

With potassium hydroxide; In water; acetonitrile; at 70 ℃; for 6h;

Reference yield:

1H-imidazole (288-32-4) + 2-chloro-5-trifluoromethylphenylethylene oxide (545410-66-0) → 1-(2-chloro-5-trifluoromethylphenyl)-2-(imidazol-1-yl)ethanol (545410-68-2)

Guidance literature:

With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;

upstream raw materials:

2-chloro-5-(trifluoromethyl)benzaldehyde

trimethylsulphonium iodide

Downstream raw materials:

1-(2-chloro-5-trifluoromethylphenyl)-2-(imidazol-1-yl)ethanol

Refernces