6-Methoxybenzo[b]thiophene-2-carboxylic acid

Base Information

Chemical Name:6-Methoxybenzo[b]thiophene-2-carboxylic acid
CAS No.:102539-79-7
Molecular Formula:C10H8O3S
Molecular Weight:208.238
Hs Code.:2934999090
European Community (EC) Number:830-590-2
DSSTox Substance ID:DTXSID60608066
Wikidata:Q82507172
Mol file:102539-79-7.mol

Synonyms:102539-79-7;6-Methoxybenzo[b]thiophene-2-carboxylic acid;6-Methoxy-benzo[b]thiophene-2-carboxylic acid;6-methoxy-1-benzothiophene-2-carboxylic acid;Benzo[b]thiophene-2-carboxylic acid, 6-methoxy-;MFCD07371542;6-Methoxybenzo[b]thiophene-2-carboxylicacid;SCHEMBL914782;DTXSID60608066;XTXMOIBADXDEKF-UHFFFAOYSA-N;STL474497;AKOS015917139;SB30240;6-methoxybenzothiophene-2-carboxylic acid;DB-058821;CS-0340545;Benzo[b]thiophene-2-carboxylicacid,6-methoxy-;EN300-186698;F18725;A800583;Z1269174646

Suppliers and Price of 6-Methoxybenzo[b]thiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methoxy-1-benzothiophene-2-carboxylicAcid
25mg
$ 45.00

TRC
6-Methoxy-1-benzothiophene-2-carboxylicAcid
250mg
$ 240.00

Matrix Scientific
6-Methoxy-benzo[b]thiophene-2-carboxylicacid 95%+
1g
$ 590.00

Labseeker
6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLICACID 95
1g
$ 570.00

J&W Pharmlab
6-Methoxy-benzo[b]thiophene-2-carboxylicacid 96%
100mg
$ 125.00

Crysdot
6-Methoxybenzo[b]thiophene-2-carboxylicacid 95+%
5g
$ 730.00

Chemenu
6-Methoxy-benzo[b]thiophene-2-carboxylicacid 95%
1g
$ 505.00

Chemcia Scientific
6-Methoxy-benzo[b]thiophene-2-carboxylicacid 95%
5 G
$ 995.00

Arctom
6-Methoxybenzo[b]thiophene-2-carboxylicacid 96%
5g
$ 1661.00

Arctom
6-Methoxybenzo[b]thiophene-2-carboxylicacid 96%
1g
$ 497.00

Total 22 raw suppliers

Chemical Property of 6-Methoxybenzo[b]thiophene-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.86E-07mmHg at 25°C
Melting Point:248.5-249 °C(Solv: acetone (67-64-1); benzene (71-43-2))
Refractive Index:1.673
Boiling Point:410 °C at 760 mmHg
PKA:3.58±0.30(Predicted)
Flash Point:201.8 °C
PSA：74.77000
Density:1.392 g/cm³
LogP:2.60810
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:208.01941529
Heavy Atom Count:14
Complexity:231

Purity/Quality:

99%, ^*data from raw suppliers

6-Methoxy-1-benzothiophene-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C=C(S2)C(=O)O

Technology Process of 6-Methoxybenzo[b]thiophene-2-carboxylic acid

There total 8 articles about 6-Methoxybenzo[b]thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 550998-58-8
6-methoxybenzo[b]thiophene-2-carboxylic acid methyl ester

: 102539-79-7
6-methoxybenzo[b]thiophene-2-carboxylic acid

Guidance literature:: 6-methoxybenzo[b]thiophene-2-carboxylic acid methyl ester; With methanol; sodium hydroxide; water; at 65 ℃; for 18h;

With hydrogenchloride; water; In methanol; at 0 ℃;

Reference yield: 93.0%

: 187753-62-4
ethyl 6-methoxybenzo[b]thiophene-2-carboxylate

: 102539-79-7
6-methoxybenzo[b]thiophene-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 2h;

Reference yield:

: 331-64-6
2-fluoro-4-methoxy-benzaldehyde

: 102539-79-7
6-methoxybenzo[b]thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide / 72 h / 100 °C

2: sodium hydroxide; methanol / 18 h / 65 °C

With methanol; triethylamine; sodium hydroxide; In N,N-dimethyl-formamide;