Technology Process of C44H41NO9
There total 7 articles about C44H41NO9 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 70 ℃;
for 2h;
DOI:10.1039/c2ob25821h
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane; acetonitrile / 1 h / -10 °C
2: water; sodium hydroxide / tetrahydrofuran; methanol; dichloromethane / 1 h
3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / acetonitrile / 2 h / 70 °C
With
triethylsilane; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; boron trifluoride diethyl etherate; water; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
3: Sonogashira coupling;
DOI:10.1039/c2ob25821h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / -78 °C
1.2: 0.5 h / -78 °C
1.3: 2 h / -78 - 20 °C
2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane; acetonitrile / 1 h / -10 °C
3.1: water; sodium hydroxide / tetrahydrofuran; methanol; dichloromethane / 1 h
4.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / acetonitrile / 2 h / 70 °C
With
triethylsilane; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; n-butyllithium; boron trifluoride diethyl etherate; water; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; hexane; dichloromethane; acetonitrile;
4.1: Sonogashira coupling;
DOI:10.1039/c2ob25821h
