2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

Base Information

Chemical Name:2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile
CAS No.:56915-94-7
Molecular Formula:C₁₉H₂₂N₄O
Molecular Weight:322.41
Hs Code.:

Synonyms:2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

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Chemical Property of 2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

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Technology Process of 2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

There total 3 articles about 2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107-91-5
cyanoacetic acid amide

: 56915-76-5
1-(4-(4-propylpiperazin-1-yl)phenyl)ethanone

: 109-94-4
formic acid ethyl ester

: 56915-94-7
2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

Guidance literature:: With sodium methylate; acetic acid; In tetrahydrofuran; water;

Reference yield:

: 21867-64-1
1-n-propylpiperazine

: 403-42-9
1-(4-fluorophenyl)ethanone

: 56915-94-7
2-oxo-6-[4-(4-propyl-piperazin-1-yl)-phenyl]-1,2-dihydro-pyridine-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide

2: sodium methylate; acetic acid / tetrahydrofuran; water

With sodium methylate; potassium carbonate; acetic acid; In tetrahydrofuran; water; dimethyl sulfoxide;