4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide

Base Information

• Chemical Name: 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide
• CAS No.: 1422064-48-9
• Molecular Formula: C₃₀H₂₀ClF₆N₅O₂
• Molecular Weight: 631.965
• Mol file: 1422064-48-9.mol

Synonyms:4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide

Chemical Property of 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide

There total 5 articles about 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-Trifluoromethylbenzaldehyde (455-19-6) + 4-chloro-2-[2-(hydrazinecarbonyl)phenylamino]benzohydrazide (1422064-41-2) → 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide (1422064-48-9)

Guidance literature:

With acetic acid; In ethanol; Reflux;

DOI:10.1248/cpb.c12-00516

Reference yield:

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide (1422064-48-9)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(II) oxide

2: thionyl chloride / 4 h / Reflux

3: hydrazine hydrate / butan-1-ol / 25 h / Reflux

4: acetic acid / ethanol / Reflux

With thionyl chloride; hydrazine hydrate; acetic acid; copper(II) oxide; In ethanol; butan-1-ol; 1: |Ullmann Condensation;

DOI:10.1248/cpb.c12-00516

Reference yield:

2,4 dichlorobenzoic acid (50-84-0) → 4-chloro-N'-[4-(trifluoromethyl)benzylidene]-2-{2-[2-(4-trifluoromethylbenzylidene)hydrazinecarbonyl]phenylamino}benzohydrazide (1422064-48-9)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(II) oxide

2: thionyl chloride / 4 h / Reflux

3: hydrazine hydrate / butan-1-ol / 25 h / Reflux

4: acetic acid / ethanol / Reflux

With thionyl chloride; hydrazine hydrate; acetic acid; copper(II) oxide; In ethanol; butan-1-ol; 1: |Ullmann Condensation;

DOI:10.1248/cpb.c12-00516

upstream raw materials:

2,4 dichlorobenzoic acid

anthranilic acid

4-Trifluoromethylbenzaldehyde

4-chloro-2-[2-(hydrazinecarbonyl)phenylamino]benzohydrazide