3-methyl-1-tosylindoline

Base Information

• Chemical Name: 3-methyl-1-tosylindoline
• CAS No.: 1403266-87-4
• Molecular Formula: C₁₆H₁₇NO₂S
• Molecular Weight: 287.382
• Mol file: 1403266-87-4.mol

Synonyms:3-methyl-1-tosylindoline

Chemical Property of 3-methyl-1-tosylindoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methyl-1-tosylindoline

There total 3 articles about 3-methyl-1-tosylindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C16H16BrNO2S → 3-methyl-1-tosylindoline (1403266-87-4)

Guidance literature:

With (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; tris-(trimethylsilyl)silane; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 10h; Irradiation;

DOI:10.1021/acscatal.6b01914

Reference yield: 82.0%

3-methyl-2,3-dihydro-1H-indole (4375-15-9) + p-toluenesulfonyl chloride (98-59-9) → 3-methyl-1-tosylindoline (1403266-87-4)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1002/chem.201705202

Reference yield: 71.0%

N-allyl-N-(2-iodophenyl)-4-methylbenzenesulfonamide (850331-71-4) → 3-methyl-1-tosylindoline (1403266-87-4)

Guidance literature:

With formic acid; tributyl-amine; fac-tris[2-phenylpyridinato-C²,N]iridium(III); In acetonitrile; at 25 - 30 ℃; for 48h; Inert atmosphere; Irradiation;

DOI:10.1038/nchem.1452

upstream raw materials:

N-allyl-N-(2-iodophenyl)-4-methylbenzenesulfonamide

3-methyl-2,3-dihydro-1H-indole

p-toluenesulfonyl chloride

Downstream raw materials:

3-Methylindole