2-Methoxybenzoic benzylidenehydrazide

Base Information

• Chemical Name: 2-Methoxybenzoic benzylidenehydrazide
• CAS No.: 86268-08-8
• Molecular Formula: C₁₅H₁₄N₂O₂
• Molecular Weight: 254.288
• European Community (EC) Number: 668-209-5
• Mol file: 86268-08-8.mol

Synonyms:AKOS000987380;(E)-N'-Benzylidene-2-methoxybenzohydrazide;2-METHOXYBENZOIC BENZYLIDENEHYDRAZIDE;Z56754030

Chemical Property of 2-Methoxybenzoic benzylidenehydrazide

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.105527694
• Heavy Atom Count: 19
• Complexity: 311

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1C(=O)NN=CC2=CC=CC=C2
• Isomeric SMILES: COC1=CC=CC=C1C(=O)N/N=C/C2=CC=CC=C2

Technology Process of 2-Methoxybenzoic benzylidenehydrazide

There total 2 articles about 2-Methoxybenzoic benzylidenehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxybenzoylhydrazine (7466-54-8) + benzaldehyde (100-52-7) → 2-methoxy-benzoic acid benzylidenehydrazide (86268-08-8)

Guidance literature:

With acetic acid; In methanol; for 3h;

DOI:10.1007/s10822-013-9692-0

Reference yield:

→ 2-methoxy-benzoic acid benzylidenehydrazide (86268-08-8)

Guidance literature:

/BRN= 2725227/;

Reference yield: 71.0%

2-methoxy-benzoic acid benzylidenehydrazide (86268-08-8) → 2-[2-(methyloxyl)phenyl]-5-phenyl-1,3,4-oxadiazole (1874-42-6)

Guidance literature:

With lead dioxide; In acetic acid; at 90 - 100 ℃; for 0.5h;

upstream raw materials:

2-methoxybenzoylhydrazine

benzaldehyde

Downstream raw materials:

2-[2-(methyloxyl)phenyl]-5-phenyl-1,3,4-oxadiazole