tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate

Base Information

• Chemical Name: tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate
• CAS No.: 620594-03-8
• Molecular Formula: C₂₄H₃₁N₃O₆
• Molecular Weight: 457.527
• Mol file: 620594-03-8.mol

Synonyms:tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate

Chemical Property of tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate

There total 1 articles about tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (4-amino-3,5-diisopropylphenyl)carbamate (437763-60-5) + 4-Nitrophenyl chloroformate (7693-46-1) → tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate (620594-03-8)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.bmcl.2009.01.020

Reference yield:

tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate (620594-03-8) + C20H26N2O2 → N-{[1-(3-methoxyphenyl)-4-(3-methoxyphenyl)-piperidin-4-yl]methyl}-N'-(4-tert-butoxycarbonylamino-2,6-diisopropylphenyl)urea

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.bmcl.2009.01.020

Reference yield:

tert-butyl 4-nitrophenyl (2,6-diisopropyl-1,4-phenylene)biscarbamate (620594-03-8) + C26H30N2O2 → N-{[1-(2-benzyloxyphenyl)-4-(3-methoxyphenyl)piperidin-4-yl]methyl}-N'-(4-tert-butoxycarbonylamino-2,6-diisopropylphenyl)urea

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.bmc.2009.04.059

upstream raw materials:

tert-butyl (4-amino-3,5-diisopropylphenyl)carbamate

4-Nitrophenyl chloroformate

Downstream raw materials:

N-{[1-phenyl-4-(3-methoxyphenyl)piperidin-4-yl]methyl}-N'-(4-tert-butoxycarbonylamino-2,6-diisopropylphenyl)urea