5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

Base Information

Chemical Name:5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide
CAS No.:1425052-41-0
Molecular Formula:C₂₁H₂₀F₇NO₂
Molecular Weight:451.384
Hs Code.:

Synonyms:5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

Chemical Property:

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Technology Process of 5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

There total 3 articles about 5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 651-83-2
4-trifluoromethyl-2,3,5,6-tetrafluoroaniline

: 443924-78-5,443924-79-6,106579-88-8
5-(2,5-dimethylphenoxy)-2-methylpentanoic acid

: 1425052-41-0
5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

Guidance literature:: With oxalyl dichloride; In toluene; at 0 - 20 ℃; for 12.5h; Reflux; Inert atmosphere;
DOI:10.1021/ja400648w

Reference yield:

: 651-83-2
4-trifluoromethyl-2,3,5,6-tetrafluoroaniline

: 443924-77-4
5-(2,5-dimethylphenoxy)-2-methylpentanoic acid chloride

: 1425052-41-0
5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

Guidance literature:: In toluene; Reflux;
DOI:10.1021/ja508165a

Reference yield:

: 443924-78-5,443924-79-6,106579-88-8
5-(2,5-dimethylphenoxy)-2-methylpentanoic acid

: 1425052-41-0
5-(2,5-dimethylphenoxy)-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 0 - 20 °C

2: toluene / Reflux

With oxalyl dichloride; In dichloromethane; toluene;
DOI:10.1021/ja508165a