(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Base Information

Chemical Name:(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid
CAS No.:1393598-09-8
Molecular Formula:C₅₃H₆₅N₃O₆S₃
Molecular Weight:936.314
Hs Code.:

Synonyms:(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Suppliers and Price of (E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

There total 6 articles about (E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1393598-06-5
7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophene-2-carbaldehyde

: 372-09-8
cyanoacetic acid

: 1393598-09-8
(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: 7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophene-2-carbaldehyde; cyanoacetic acid; With piperidine; In chloroform; at 85 ℃; for 18h; Sealed tube; Inert atmosphere;

With hydrogenchloride; In chloroform; water; Inert atmosphere; Sealed tube;
DOI:10.1021/ol301730c

Reference yield:

: 1158909-71-7
N,N-di(4-n-hexyloxyphenyl)amine

: 1393598-09-8
(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: tri-tert-butyl phosphine; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / toluene / Inert atmosphere; Reflux

2.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 20 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere

4.1: piperidine / chloroform / 18 h / 85 °C / Sealed tube; Inert atmosphere

4.2: Inert atmosphere; Sealed tube

With piperidine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; tri-tert-butyl phosphine; sodium t-butanolate; In tetrahydrofuran; hexane; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol301730c

Reference yield:

: 1393598-02-1
4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophene-2-carbaldehyde

: 1393598-09-8
(E)-3-(7-(2-(bis(4-(hexyloxy)phenyl)amino)thiazol-5-yl)-4,5-bis(hexyloxy)benzo[1,2-b:4,3-b']dithiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / 2 h / 20 °C / Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere

3.1: piperidine / chloroform / 18 h / 85 °C / Sealed tube; Inert atmosphere

3.2: Inert atmosphere; Sealed tube

With piperidine; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/ol301730c