(4-BROMOANILINOMETHYLENE)MALONIC ACID DIETHYL ESTER

Base Information

• Chemical Name: (4-BROMOANILINOMETHYLENE)MALONIC ACID DIETHYL ESTER
• CAS No.: 101937-44-4
• Molecular Formula: C14H16 Br N O4
• Molecular Weight: 342.189
• Hs Code.: 2922499990
• Mol file: 101937-44-4.mol

Synonyms:Malonicacid, (p-bromoanilinomethylene)-, diethyl ester (6CI); Propanedioic acid, [[(4-bromophenyl)amino]methylene]-,diethyl ester (9CI); 2-[(4-Bromophenylamino)methylene]malonic acid diethylester

Chemical Property of (4-BROMOANILINOMETHYLENE)MALONIC ACID DIETHYL ESTER

Chemical Property:

• Vapor Pressure: 8.37E-06mmHg at 25°C
• Melting Point: 100-101 °C
• Refractive Index: 1.573
• Boiling Point: 374.4°C at 760 mmHg
• PKA: -1.61±0.70(Predicted)
• Flash Point: 180.2°C
• PSA: 64.63000
• Density: 1.419g/cm³
• LogP: 2.94410
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Diethyl2-(((4-Bromophenyl)amino)methylene)malonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-BROMOANILINOMETHYLENE)MALONIC ACID DIETHYL ESTER

There total 4 articles about (4-BROMOANILINOMETHYLENE)MALONIC ACID DIETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diethyl 2-ethoxymethylenemalonate (87-13-8) + 4-bromo-aniline (106-40-1) → diethyl 2-((4-bromophenylamino)methylene)malonate (101937-44-4)

Guidance literature:

for 0.0416667h; Irradiation;

Reference yield:

diethyl methoxymethylenemalonate (40131-09-7) + 4-bromo-aniline (106-40-1) → diethyl 2-((4-bromophenylamino)methylene)malonate (101937-44-4)

Guidance literature:

at 150 ℃; for 3h; Sealed tube;

Reference yield:

diethyl (anilinomethylene)malonate (54535-22-7) → diethyl 2-((4-bromophenylamino)methylene)malonate (101937-44-4)

Guidance literature:

With bromine; acetic acid;

upstream raw materials:

diethyl (anilinomethylene)malonate

diethyl 2-ethoxymethylenemalonate

4-bromo-aniline

diethyl methoxymethylenemalonate

Downstream raw materials:

6-bromo-4-hydroxyquinoline-3-carboxylic acid ethyl ester

ethyl 6-bromo-4-oxo-1,4-dihydro-quinoline-3-carboxylate

6-bromo-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

6-bromo-4-chloroquinoline-3-carbaldehyde