5-(2-Methylpropyl)thiophene-2-carboxylic acid

Base Information

Chemical Name:5-(2-Methylpropyl)thiophene-2-carboxylic acid
CAS No.:5681-91-4
Molecular Formula:C₉H₁₂O₂S
Molecular Weight:184.259
Hs Code.:
European Community (EC) Number:835-048-9

Synonyms:5681-91-4;5-(2-methylpropyl)thiophene-2-carboxylic acid;5-ISOBUTYLTHIOPHENE-2-CARBOXYLIC ACID;5-Isobutyl-thiophene-2-carboxylic acid;MFCD01211014;SCHEMBL261525;QKSXJQJLJNLEPE-UHFFFAOYSA-N;BBL040752;STK351001;AKOS000313738;NCGC00335760-01;DB-340908;5-ISOBUTYL-2-THIOPHENECARBOXYLIC ACID;CS-0264358;5-(2-methylpropyl)thiophene-2-carboxylicacid;EN300-92647;G45834;AB01328522-02;Z1171157980

Suppliers and Price of 5-(2-Methylpropyl)thiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-isobutylthiophene-2-carboxylicacid
25mg
$ 65.00

AK Scientific
5-(2-Methylpropyl)thiophene-2-carboxylicacid
500mg
$ 519.00

Total 4 raw suppliers

Chemical Property of 5-(2-Methylpropyl)thiophene-2-carboxylic acid

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:184.05580079
Heavy Atom Count:12
Complexity:168

Purity/Quality:

97% ^*data from raw suppliers

5-isobutylthiophene-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC1=CC=C(S1)C(=O)O

Technology Process of 5-(2-Methylpropyl)thiophene-2-carboxylic acid

There total 5 articles about 5-(2-Methylpropyl)thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 527-72-0
2-thiophenylcarboxylic acid

: 78-83-1
2-methyl-propan-1-ol

: 5681-91-4
5-isobutyl-thiophene-2-carboxylic acid

Guidance literature:: 2-thiophenylcarboxylic acid; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 0.5h;

2-methyl-propan-1-ol; In tetrahydrofuran; toluene; at -78 - 20 ℃; for 21h;
DOI:10.1021/jm401456d

Reference yield:

: 78-77-3
Isobutyl bromide

: 5681-91-4
5-isobutyl-thiophene-2-carboxylic acid

Guidance literature:: 2-thiophenylcarboxylic acid; With n-butyllithium; In tetrahydrofuran; pentane; at -78 ℃; for 0.5h;

Isobutyl bromide; In tetrahydrofuran; pentane; at -78 - 20 ℃; for 21h;

Reference yield:

: 527-72-0
2-thiophenylcarboxylic acid

: 78-77-3
Isobutyl bromide

: 5681-91-4
5-isobutyl-thiophene-2-carboxylic acid

Guidance literature:: 2-thiophenylcarboxylic acid; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃;

Isobutyl bromide; In tetrahydrofuran; pentane; at -78 - 20 ℃; for 21h;

In tetrahydrofuran; pentane; Acidic aqueous solution;