1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane

Base Information

• Chemical Name: 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane
• CAS No.: 177597-25-0
• Molecular Formula: C₁₉H₂₅BrN₂O₃
• Molecular Weight: 409.323
• Mol file: 177597-25-0.mol

Synonyms:1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane

Chemical Property of 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane

There total 4 articles about 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-nitrophenol (5847-59-6) → 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane (177597-25-0)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / dimethylformamide / 85 °C

2: acetonitrile; ethanol / Heating

3: H₂ / 10 percent Pd/C / methanol / Ambient temperature

With hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/S0960-894X(98)00689-1

Reference yield:

1-(2-bromo-4-nitrophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane (177597-24-9) → 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane (177597-25-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; Ambient temperature;

DOI:10.1016/S0960-894X(98)00689-1

Reference yield:

N-methylhomoveratrylamine (3490-06-0) → 1-(2-bromo-4-aminophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane (177597-25-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile; ethanol / Heating

2: H₂ / 10 percent Pd/C / methanol / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; ethanol; acetonitrile;

DOI:10.1016/S0960-894X(98)00689-1

upstream raw materials:

1-(2-bromo-4-nitrophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane

N-methylhomoveratrylamine

2-bromo-4-nitrophenol

2-bromo-1-(2-bromoethoxy)-4-nitrobenzene

Downstream raw materials:

1-(2-bromo-4-nitrophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane