Technology Process of 1-(1-benzyl-piperidin-4-yl)-3-4-(methylsulfinyl)butyl thiourea
There total 4 articles about 1-(1-benzyl-piperidin-4-yl)-3-4-(methylsulfinyl)butyl thiourea which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
dichloromethane;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2.1: dihydrogen peroxide / 2,2,2-trifluoroethanol / 1.33 h / 0 - 20 °C / Inert atmosphere
3.1: triethylamine / ethanol / 0.5 h / 20 °C / Inert atmosphere
3.2: 2.25 h / 0 - 20 °C
4.1: dichloromethane / 1 h / Reflux
With
lithium aluminium tetrahydride; dihydrogen peroxide; triethylamine;
In
diethyl ether; ethanol; dichloromethane; 2,2,2-trifluoroethanol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dihydrogen peroxide / 2,2,2-trifluoroethanol / 1.33 h / 0 - 20 °C / Inert atmosphere
2.1: triethylamine / ethanol / 0.5 h / 20 °C / Inert atmosphere
2.2: 2.25 h / 0 - 20 °C
3.1: dichloromethane / 1 h / Reflux
With
dihydrogen peroxide; triethylamine;
In
ethanol; dichloromethane; 2,2,2-trifluoroethanol;
