4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Base Information

Chemical Name:4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole
CAS No.:365530-09-2
Molecular Formula:C₁₇H₁₄F₃N₃O₃
Molecular Weight:365.312
Hs Code.:

Synonyms:4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Suppliers and Price of 4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

There total 1 articles about 4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 720-94-5
4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

: 100-16-3
4-nitrophenylhydrazone

: 365530-09-2
4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Guidance literature:: In ethanol; for 20h; Heating;
DOI:10.1021/jm010153c

Reference yield: 52.0%

: 365530-09-2
4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

: 473576-14-6
3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

Guidance literature:: With acetic acid; for 2h; Heating;
DOI:10.1021/jm010153c

Reference yield:

: 365530-09-2
4,5-dihydro-5-hydroxy-3-(4-methylphenyl)-1-(4-nitrophenyl)-5-trifluoromethylpyrazole

: 365530-11-6
1-(4-aminophenyl)-3-(4-methylphenyl)-5-trifuoromethylpyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / AcOH / 2 h / Heating

2: 51 percent / hydrazine hydrate / Pd/C / aq. ethanol / 0.75 h / Heating

With hydrazine hydrate; acetic acid; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm010153c