2,3-Dichlorobicyclo[2.2.1]heptane

Base Information

• Chemical Name: 2,3-Dichlorobicyclo[2.2.1]heptane
• CAS No.: 101011-90-9
• Molecular Formula: C₇H₁₀Cl₂
• Molecular Weight: 165.062
• European Community (EC) Number: 621-619-8
• Mol file: 101011-90-9.mol

Synonyms:2,3-dichlorobicyclo[2.2.1]heptane;Bicyclo[2.2.1]heptane, 2,3-dichloro- (9CI);101011-90-9;89577-09-3;2,3-dichloronorbornane;SCHEMBL4136641;Bicyclo[2.2.1]heptane, 2,3-dichloro-, (endo,endo)- (9CI);AKOS024331639;Bicyclo[2.2.1]heptane,2,3-dichloro-,(endo,endo)-(9ci)

Chemical Property of 2,3-Dichlorobicyclo[2.2.1]heptane

Chemical Property:

• Boiling Point: 72 - 74 °C (7 mmHg)
• PSA: 0.00000
• LogP: 2.63110
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 164.0159557
• Heavy Atom Count: 9
• Complexity: 110

Purity/Quality:

2,3-DICHLORO-BICYCLO[2.2.1]HEPTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2CC1C(C2Cl)Cl

Technology Process of 2,3-Dichlorobicyclo[2.2.1]heptane

There total 8 articles about 2,3-Dichlorobicyclo[2.2.1]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

norborn-2-ene (498-66-8) → trans-2,3-Dichlornorbornan (101011-90-9)

Guidance literature:

With manganese(IV) oxide; acetyl chloride; manganese(ll) chloride; In N,N-dimethyl-formamide; at 30 ℃; for 1h;

DOI:10.1080/00397919108016774

Reference yield: 33.0%

norborn-2-ene (498-66-8) + acetic anhydride (108-24-7) → trans-2,3-Dichlornorbornan (2843-43-8,14627-75-9,89577-09-3,101011-90-9) + endo-2,endo-3-dichloronorbornane (14627-75-9) + trans-2-Acetoxy-3-chloronorbornane (93955-44-3)

Guidance literature:

With Nitryl chloride;

Reference yield: 19.0%

norborn-2-ene (498-66-8) → trans-2,3-Dichlornorbornan (2843-43-8,14627-75-9,89577-09-3,101011-90-9) + endo-2,endo-3-dichloronorbornane (14627-75-9)

Guidance literature:

With Mn(IV)(N,N'-disalicylidene-1,3-diaminopropane^(2-))Cl₂; In dichloromethane; at 20 ℃;

DOI:10.1039/c39950002015

upstream raw materials:

norborn-2-ene

norbornene

trans-5,6-dichlorobicyclo<2.2.1>hept-2-ene

acetic anhydride

Refernces

• 1、 Mohammed, Abdulkarim H. A.,Nagendrappa, Gopalpur. "Generation of nitryl chloride from chlorotrimethylsilane-acetyl nitrate reaction: A one-pot preparation of gem-chloronitro compounds from oximes". . p. 571 - 577. Retrieved 2010.
• 2、 Zyk,Bondarenko,Nesterov,Zefirov. "Addition reactions of nitryl chloride at multiple bonds". . p. 980 - 986. Retrieved 2007/10/03.
• 3、 Bellesia, Franco,Boni, Monica,Ghelfi, Franco,Grandi, Romano,Pagnoni, Ugo M.,Pinetti, Adriano. "Acetal Chlorination with MnO2-Trimethylchlorosilane". . p. 4579 - 4586. Retrieved 2007/10/02.