Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester
CAS No.:100928-04-9
Molecular Formula:C26H44 O4 S Si
Molecular Weight:480.784
Hs Code.:
Mol file:100928-04-9.mol

Synonyms:1H-Indene-1-ethanol,4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]octahydro-b,7a-dimethyl-, 4-methylbenzenesulfonate, (bS,1R,3aR,4S,7aR)- (9CI);1H-Indene-1-ethanol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]octahydro-b,7a-dimethyl-,4-methylbenzenesulfonate, [1R-[1a(S*),3ab,4a,7aa]]-

Suppliers and Price of Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 10 raw suppliers

Chemical Property of Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester

Chemical Property:

Refractive Index:1.52
Boiling Point:521.6±23.0 °C(Predicted)
PSA：60.98000
Density:1.07±0.1 g/cm3(Predicted)
LogP:8.02400

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester

There total 12 articles about Toluene-4-sulfonic acid2-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 66774-80-9,111924-49-3
(S)-2-((3R,3aR,7S,7aR)-octahydro-7-hydroxy-3a-methyl-1H-inden-3-yl)propyl 4-methylbenzenesulfonate

: 69739-34-0
t-butyldimethylsiyl triflate

: 100928-04-9
(S)-2-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)propyl 4-methylbenzenesulfonate

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at -40 ℃; Inert atmosphere;
DOI:10.3987/COM-09-11871

Reference yield: 95.0%

: 100928-03-8,215509-33-4
(S)-2-((1R,3aR,4S,7aR)-4-(tert-butyldimethylsilyloxy)-7a-methyloctahydro-1H-inden-1-yl)propan-1-ol

: 98-59-9
p-toluenesulfonyl chloride

: 100928-04-9
(S)-2-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)propyl 4-methylbenzenesulfonate

Guidance literature:: With pyridine; at 0 - 20 ℃; for 23h;
DOI:10.1021/jo00366a004

Reference yield: 85.0%

: 66774-80-9,111924-49-3
(S)-2-((3R,3aR,7S,7aR)-octahydro-7-hydroxy-3a-methyl-1H-inden-3-yl)propyl 4-methylbenzenesulfonate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 100928-04-9
(S)-2-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)propyl 4-methylbenzenesulfonate

Guidance literature:: With 1H-imidazole; In dichloromethane; N,N-dimethyl-formamide; a.) r.t., 24 h, b.) 55 deg C, 30 h;
DOI:10.1021/jo00037a039