4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine

Base Information

Chemical Name:4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine
CAS No.:869709-83-1
Molecular Formula:C₁₃H₉ClN₂OS
Molecular Weight:276.746
Hs Code.:
European Community (EC) Number:823-533-8
ChEMBL ID:CHEMBL1556925
Mol file:869709-83-1.mol

Synonyms:4-chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine;869709-83-1;MLS001176708;CHEMBL1556925;SCHEMBL15703517;MFCD04973911;AKOS001137595;SMR000592387;CS-0234680;EN300-14552;Z104341502

Suppliers and Price of 4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine 97%
1g
$ 376.00

Chemenu
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine 97%
1g
$ 355.00

AK Scientific
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine
500mg
$ 271.00

AK Scientific
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine
250mg
$ 194.00

Total 5 raw suppliers

Chemical Property of 4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:276.0124118
Heavy Atom Count:18
Complexity:286

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC3=C(S2)C(=NC=N3)Cl

Technology Process of 4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine

There total 10 articles about 4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 225385-22-8
6-(4-Methoxyphenyl)thieno[3,2-d] pyrimidin-4(3H)-one

: 869709-83-1
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d] pyrimidine

Guidance literature:: With N,N-dimethyl-formamide; trichlorophosphate; at 110 ℃; for 6h;
DOI:10.1021/acs.jmedchem.8b01391

Reference yield: 25.7%

: 225385-22-8
6-(4-Methoxyphenyl)thieno[3,2-d] pyrimidin-4(3H)-one

: 37572-24-0
3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylic acid ethyl ester

: 869709-83-1
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d] pyrimidine

Guidance literature:: With sodium carbonate; In trichlorophosphate;

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 869709-83-1
4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d] pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: sodium acetate; trichlorophosphate / N,N-dimethyl-formamide

2: sodium hydroxide / ethanol; water

3: acetic anhydride; formic acid; sodium carbonate / water

4: ammonium formate; formamide

5: sodium carbonate / trichlorophosphate

With sodium hydroxide; formic acid; sodium acetate; ammonium formate; acetic anhydride; sodium carbonate; formamide; trichlorophosphate; In ethanol; water; N,N-dimethyl-formamide; trichlorophosphate;