methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Base Information

Chemical Name:methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate
CAS No.:1429764-27-1
Molecular Formula:C₁₉H₁₆BrNO₅S₂
Molecular Weight:482.376
Hs Code.:

Synonyms:methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Suppliers and Price of methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

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Technology Process of methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

There total 5 articles about methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1429764-30-6
methyl 2-((4-(4-bromophenylsulfonamido)-1-methoxynaphthalen-2-yl)thio)acetate?

: 1429764-27-1
methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Guidance literature:: methyl 2-((4-(4-bromophenylsulfonamido)-1-methoxynaphthalen-2-yl)thio)acetate?; With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

With methanol; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jm500010b

Reference yield:

: 4900-63-4
1-methoxy-4-nitronaphthalene

: 1429764-27-1
methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: N-iodo-succinimide; trifluoroacetic acid / 20 h / Reflux; Inert atmosphere

2.1: zinc(II) chloride; caesium carbonate / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

2.2: 20 h / 60 °C / Inert atmosphere

3.1: iron; acetic acid / 1 h / 70 °C

3.2: 20 °C

4.1: methanol; boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

With methanol; N-iodo-succinimide; boron tribromide; iron; caesium carbonate; acetic acid; trifluoroacetic acid; zinc(II) chloride; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1429765-70-7
2-iodo-1-methoxy-4-nitronaphthalene

: 1429764-27-1
methyl 2-((4-(4-bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: zinc(II) chloride; caesium carbonate / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

1.2: 20 h / 60 °C / Inert atmosphere

2.1: iron; acetic acid / 1 h / 70 °C

2.2: 20 °C

3.1: methanol; boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

With methanol; boron tribromide; iron; caesium carbonate; acetic acid; zinc(II) chloride; In tetrahydrofuran; dichloromethane;