(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Base Information

Chemical Name:(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol
CAS No.:143347-70-0
Molecular Formula:C₂₄H₃₄O₃Si
Molecular Weight:398.618
Hs Code.:

Synonyms:(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Suppliers and Price of (1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

There total 6 articles about (1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 143347-69-7
(1R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxy)-3-methoxy-cyclohexanecarboxylic acid methyl ester

: 143347-70-0
(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃;
DOI:10.1021/jo00045a013

Reference yield:

: 5709-98-8
(R)-cyclohex-3-enecarboxylic acid

: 143347-70-0
(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Guidance literature:: Multi-step reaction with 5 steps

1: 1) MCPBA, 2) Et₃N, SiO₂ / 1) CCl₄, 0 to 25 deg C, 2) 70 deg C

2: 90 percent / imidazole / dimethylformamide / 25 °C

3: NaHCO₃ / 25 °C

4: 2,6-di-tert-butylpyridine / CH₂Cl₂ / 25 °C

5: 100 percent / LiAlH₄ / diethyl ether / 0 °C

With 1H-imidazole; lithium aluminium tetrahydride; 2,6-di-tert-butyl-pyridine; silica gel; sodium hydrogencarbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00045a013

Reference yield:

: 116498-92-1
(1R,4R,5R)-4-hydroxy-6-oxabicyclo[3.2.1]octan-7-one

: 143347-70-0
(1R,3R,4R)-4-[((1,1-dimethylethyl)diphenylsilyl)-oxy]-3-methoxy-cyclohexanemethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / imidazole / dimethylformamide / 25 °C

2: NaHCO₃ / 25 °C

3: 2,6-di-tert-butylpyridine / CH₂Cl₂ / 25 °C

4: 100 percent / LiAlH₄ / diethyl ether / 0 °C

With 1H-imidazole; lithium aluminium tetrahydride; 2,6-di-tert-butyl-pyridine; sodium hydrogencarbonate; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00045a013