2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide

Base Information

• Chemical Name: 2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide
• CAS No.: 82605-23-0
• Molecular Formula: C₂₄H₂₈N₂O₂
• Molecular Weight: 376.499
• Mol file: 82605-23-0.mol

Synonyms:2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide

Chemical Property of 2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide

There total 1 articles about 2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyltryptamine (4307-98-6) + 3,6-dimethyl-3,4-dihydro-2-pyrone (20155-55-9) → 2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide (82605-23-0)

Guidance literature:

In benzene; for 22h; Heating;

DOI:10.1007/BF00762054

Reference yield: 92.0%

2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide (82605-23-0) → 12-Benzyl-3,12b-dimethyl-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one (82605-31-0)

Guidance literature:

With hydrogenchloride; In methanol; Heating;

DOI:10.1007/BF00762054

Reference yield:

2-Methyl-5-oxo-hexanoic acid [2-(1-benzyl-1H-indol-3-yl)-ethyl]-amide (82605-23-0) → STOCK1N-05032 (82605-39-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / aq. HCl / methanol / Heating

2: 71.2 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 20 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; methanol; diethyl ether;

DOI:10.1007/BF00762054

upstream raw materials:

N-benzyltryptamine

3,6-dimethyl-3,4-dihydro-2-pyrone

Downstream raw materials:

12-Benzyl-3,12b-dimethyl-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one

STOCK₁N-05032