C₅₀H₆₀N₄O₁₂

Base Information

• Chemical Name: C₅₀H₆₀N₄O₁₂
• CAS No.: 1290540-75-8
• Molecular Formula: C₅₀H₆₀N₄O₁₂
• Molecular Weight: 909.046
• Mol file: 1290540-75-8.mol

Synonyms:C₅₀H₆₀N₄O₁₂

Chemical Property of C₅₀H₆₀N₄O₁₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₀H₆₀N₄O₁₂

There total 3 articles about C₅₀H₆₀N₄O₁₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

propylamine (107-10-8,42939-71-9) + C47H53N3O13 (1290540-74-7) → C50H60N4O12 (1290540-75-8)

Guidance literature:

C₄₇H₅₃N₃O₁₃; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

propylamine; With triethylamine; In dichloromethane; at 25 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol200408j

Reference yield:

2-(4'-dimethylamino-2'-hydroxybenzoyl)benzoic acid (24460-11-5) → C50H60N4O12 (1290540-75-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / 48 h / 95 °C / Sealed tube; Inert atmosphere

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 0 °C / Inert atmosphere

2.2: 12 h / 25 °C / Inert atmosphere

With oxalyl dichloride; N,N-dimethyl-formamide; trifluoroacetic acid; In dichloromethane;

DOI:10.1021/ol200408j

Reference yield:

1-<2-bis(ethoxycarbonylmethyl)amino-4-hydroxyphenoxy>-2-<2-bis(ethoxycarbonylmethyl)amino-5-methylphenoxy>ethane (103471-69-8) → C50H60N4O12 (1290540-75-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / 48 h / 95 °C / Sealed tube; Inert atmosphere

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 0 °C / Inert atmosphere

2.2: 12 h / 25 °C / Inert atmosphere

With oxalyl dichloride; N,N-dimethyl-formamide; trifluoroacetic acid; In dichloromethane;

DOI:10.1021/ol200408j

upstream raw materials:

propylamine

C₄₇H₅₃N₃O₁₃

2-(4'-dimethylamino-2'-hydroxybenzoyl)benzoic acid

1-<2-bis(ethoxycarbonylmethyl)amino-4-hydroxyphenoxy>-2-<2-bis(ethoxycarbonylmethyl)amino-5-methylphenoxy>ethane