3alpha-Hydroxytibolone

Base Information

Chemical Name:3alpha-Hydroxytibolone
CAS No.:100239-44-9
Molecular Formula:C21H30 O2
Molecular Weight:314.46
Hs Code.:
UNII:37T303O94A
DSSTox Substance ID:DTXSID001315905
Nikkaji Number:J826.154G
Wikipedia:3%CE%B1-Hydroxytibolone
Mol file:100239-44-9.mol

Synonyms:3-hydroxytibolone;3alpha-hydroxytibolone;3alpha-Tib;3beta-hydroxytibolone;3beta-Tib

Suppliers and Price of 3alpha-Hydroxytibolone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
3a-Hydroxytibolone
5 mg
$ 2120.00

American Custom Chemicals Corporation
3A-HYDROXYTIBOLONE 95.00%
10MG
$ 1871.10

American Custom Chemicals Corporation
3A-HYDROXYTIBOLONE 95.00%
1MG
$ 739.20

Total 4 raw suppliers

Chemical Property of 3alpha-Hydroxytibolone

Chemical Property:

Melting Point:72-74°C
Refractive Index:1.578
PSA：40.46000
LogP:3.67440
Storage Temp.:Controlled Substance, -20?C Freezer
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:314.224580195
Heavy Atom Count:23
Complexity:596

Purity/Quality:

99% ^*data from raw suppliers

3a-Hydroxytibolone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(CCC(C2)O)C3C1C4CCC(C4(CC3)C)(C#C)O
Isomeric SMILES:C[C@@H]1CC2=C(CC[C@H](C2)O)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O
Uses As a metabolite of Tibolone, 3α-Hydroxy Tibolone can be used as a synthetic steroid with weak estrogenic, androgenic and progestogenic activity and a pharamceutical used in the treatment of menopausal syndrome.

Technology Process of 3alpha-Hydroxytibolone

There total 5 articles about 3alpha-Hydroxytibolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 500019-09-0
17α-ethynyl-17β-hydroxy-7α-methyl-5(10)-estren-α3-yl acetate

: 100239-44-9
3alpha-Hydroxytibolone

Guidance literature:: With potassium carbonate; In methanol; water; at 20 ℃; for 3h;
DOI:10.1016/S0957-4166(02)00712-7

Reference yield: 70.0%

: 5630-53-5
tibolone

: 100239-44-9
3alpha-Hydroxytibolone

: 100239-45-0
(3β,7α,17α)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3,17-diol

Guidance literature:: With lithium tri(t-butoxy)aluminum hydride; In tetrahydrofuran; at -70 ℃; for 2h;
DOI:10.1002/mrc.1064

Reference yield:

: 5630-53-5
tibolone

: 100239-44-9
3alpha-Hydroxytibolone

Guidance literature:: With D-glucose; Kluyveromyces lactis CBS 2359; In phosphate buffer; at 28 ℃; for 48h; pH=6.0;
DOI:10.1016/j.steroids.2007.09.008