Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester

Base Information

• Chemical Name: Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester
• CAS No.: 215313-34-1
• Molecular Formula: C₇₂H₁₂₂N₂O₁₁S
• Molecular Weight: 1223.83

Synonyms:Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester

Chemical Property of Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester

There total 5 articles about Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(S)-tryptophan methyl ester hydrochloride (7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8) + cyclohexan-2-on-1-yl 2,3,4,6-tetra-O-lauroyl-1-thio-β-D-galactopyranoside (215312-94-0) → Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester (215313-34-1)

Guidance literature:

With sodium cyanoborohydride; In tetrahydrofuran; acetonitrile; for 73h;

DOI:10.1016/S0968-0896(98)00087-X

Reference yield:

n-dodecanoyl chloride (112-16-3) → Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester (215313-34-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / DMAP / pyridine; pentane / 40 h / Ambient temperature

2: 77 percent / CF₃SO₃SiMe₃ / CH₂Cl₂ / 48 h

3: 94 percent / Et₂NH / CH₂Cl₂ / 3 h

4: 92 percent / NaCNBH₃ / acetonitrile; tetrahydrofuran / 73 h

With dmap; trimethylsilyl trifluoromethanesulfonate; sodium cyanoborohydride; diethylamine; In tetrahydrofuran; pyridine; dichloromethane; acetonitrile; pentane;

DOI:10.1016/S0968-0896(98)00087-X

Reference yield:

D-Galactose (10257-28-0) → Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester (215313-34-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / DMAP / pyridine; pentane / 40 h / Ambient temperature

2: 77 percent / CF₃SO₃SiMe₃ / CH₂Cl₂ / 48 h

3: 94 percent / Et₂NH / CH₂Cl₂ / 3 h

4: 92 percent / NaCNBH₃ / acetonitrile; tetrahydrofuran / 73 h

With dmap; trimethylsilyl trifluoromethanesulfonate; sodium cyanoborohydride; diethylamine; In tetrahydrofuran; pyridine; dichloromethane; acetonitrile; pentane;

DOI:10.1016/S0968-0896(98)00087-X

upstream raw materials:

(S)-tryptophan methyl ester hydrochloride

cyclohexan-2-on-1-yl 2,3,4,6-tetra-O-lauroyl-1-thio-β-D-galactopyranoside

n-dodecanoyl chloride

D-Galactose

Downstream raw materials:

(S)-3-(1H-Indol-3-yl)-2-[2-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-cyclohexylamino]-propionic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 215313-34-1 Dodecanoic acid (2S,3R,4S,5S,6R)-4,5-bis-dodecanoyloxy-6-dodecanoyloxymethyl-2-{2-[(S)-2-(1H-indol-3-yl)-1-methoxycarbonyl-ethylamino]-cyclohexylsulfanyl}-tetrahydro-pyran-3-yl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send