Technology Process of 3-<(1R,S)-(3E,7E)-<10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-8-methyl-4-formyl-1-hydroxy>-3,7-decadien-1-yl>furan
There total 4 articles about 3-<(1R,S)-(3E,7E)-<10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-8-methyl-4-formyl-1-hydroxy>-3,7-decadien-1-yl>furan which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrapropylammonium perruthennate; 3 A molecular sieve; 4-methylmorpholine N-oxide;
In
dichloromethane;
for 3h;
Ambient temperature;
DOI:10.1016/S0040-4020(01)85353-9
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / diethyl ether / 1 h / Ambient temperature
2: 1.) BuLi; 2.) ammonium chloride solution / tetrahydrofuran / 0 - 50 °C / 1.) THF, 0-50 deg C, 2 h; 2.) THF, 0 deg C
3: 49 percent / ethylmagnesium bromide / benzene; diisopropyl ether / 120 h / Heating
4: 48 percent / tetra-n-propylammmonium perruthenate, crushed 3 Angstroem molecular sieves, N-methylmorpholine N-oxide / CH2Cl2 / 3 h / Ambient temperature
With
n-butyllithium; tetrapropylammonium perruthennate; 3 A molecular sieve; ethylmagnesium bromide; ammonium chloride; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; diethyl ether; dichloromethane; di-isopropyl ether; benzene;
DOI:10.1016/S0040-4020(01)85353-9
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) BuLi; 2.) ammonium chloride solution / tetrahydrofuran / 0 - 50 °C / 1.) THF, 0-50 deg C, 2 h; 2.) THF, 0 deg C
2: 49 percent / ethylmagnesium bromide / benzene; diisopropyl ether / 120 h / Heating
3: 48 percent / tetra-n-propylammmonium perruthenate, crushed 3 Angstroem molecular sieves, N-methylmorpholine N-oxide / CH2Cl2 / 3 h / Ambient temperature
With
n-butyllithium; tetrapropylammonium perruthennate; 3 A molecular sieve; ethylmagnesium bromide; ammonium chloride; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; dichloromethane; di-isopropyl ether; benzene;
DOI:10.1016/S0040-4020(01)85353-9
