3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

Base Information

• Chemical Name: 3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione
• CAS No.: 114136-64-0
• Molecular Formula: C₁₁H₅BrF₄N₂O₂
• Molecular Weight: 353.071
• Mol file: 114136-64-0.mol

Synonyms:3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

Chemical Property of 3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

There total 1 articles about 3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-fluorophenylcarbamate (2395-34-8) → 3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione (114136-64-0) + (4-bromo-2-fluorophenyl)-carbamic acid ethyl ester (214329-73-4)

Guidance literature:

With bromine;

Reference yield:

3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione (114136-64-0) + 2-aminooxysulphonyl-1,3,5-trimethylbenzene (O-mesitylenesulphonylhydroxylamine) → 1-amino-3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione (353240-65-0)

Guidance literature:

With potassium carbonate; In tetrahydrofuran;

Reference yield:

3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione (114136-64-0) → 3-(4-bromo-2-fluorophenyl)-1-methyl-6-trifluoromethyl-2,4 (1H, 3H)-pyrimidinedione + 3-(4-bromo-2-fluoro-5-nitrophenyl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione (114136-70-8)

Guidance literature:

upstream raw materials:

ethyl 2-fluorophenylcarbamate

Downstream raw materials:

1-amino-3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

3-(4-bromo-2-fluoro-5-nitrophenyl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione