ethyl N-(2-fluorophenyl)carbamate

Base Information

• Chemical Name: ethyl N-(2-fluorophenyl)carbamate
• CAS No.: 2395-34-8
• Molecular Formula: C9H10 F N O2
• Molecular Weight: 183.182
• Hs Code.: 2924299090
• NSC Number: 51599
• DSSTox Substance ID: DTXSID40946771
• Nikkaji Number: J1.074.472E
• Wikidata: Q82924457
• Mol file: 2395-34-8.mol

Synonyms:ethyl N-(2-fluorophenyl)carbamate;2395-34-8;2-Fluoro-N-ethoxycarbonylaniline;NSC51599;(2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER;SCHEMBL4826133;ethyl (2-fluorophenyl)carbamate;DTXSID40946771;NSC-51599;STK490378;AKOS003268815;(2-fluorophenyl)carbamic acid ethyl ester;Ethyl hydrogen (2-fluorophenyl)carbonimidate;N-(2-Fluorophenyl)-carbamic acid ethyl ester;J-522916;Carbonic acid, monoamide, N-(2-fluorophenyl)-, ethyl ester

Chemical Property of ethyl N-(2-fluorophenyl)carbamate

Chemical Property:

• Vapor Pressure: 0.313mmHg at 25°C
• Boiling Point: 201.1°Cat760mmHg
• Flash Point: 75.4°C
• PSA: 38.33000
• Density: 1.224g/cm³
• LogP: 2.46710
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 183.06955672
• Heavy Atom Count: 13
• Complexity: 175

Purity/Quality:

(2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NC1=CC=CC=C1F

Technology Process of ethyl N-(2-fluorophenyl)carbamate

There total 5 articles about ethyl N-(2-fluorophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Fluoroaniline (348-54-9) + chloroformic acid ethyl ester (541-41-3) → ethyl 2-fluorophenylcarbamate (2395-34-8) + pyridine hydrochloride (628-13-7)

Guidance literature:

In pyridine; hexane;

Reference yield:

2-Fluoroaniline (348-54-9) + chloroformic acid ethyl ester (541-41-3) → ethyl 2-fluorophenylcarbamate (2395-34-8)

Guidance literature:

With sodium carbonate;

DOI:10.1021/jm00334a041

Reference yield:

2-Fluoroaniline (348-54-9) → ethyl 2-fluorophenylcarbamate (2395-34-8)

Guidance literature:

With sodium hydroxide; In chloroformic acid ethyl ester;

upstream raw materials:

2-Fluoroaniline

chloroformic acid ethyl ester

N-carboethoxyaniline

Downstream raw materials:

3-(4-bromo-2-fluorophenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

(4-bromo-2-fluorophenyl)-carbamic acid ethyl ester

ethyl 4-(chlorosulfonyl)-2-fluorophenylcarbamate

ethyl 2-fluoro-4-sulfamoylphenylcarbamate