Diethyl (diethylamino)propanedioate

Base Information

Chemical Name:Diethyl (diethylamino)propanedioate
CAS No.:37706-08-4
Molecular Formula:C11H21 N O4
Molecular Weight:231.2887
Hs Code.:
NSC Number:158337
DSSTox Substance ID:DTXSID50303437
Wikidata:Q82048726
Mol file:37706-08-4.mol

Synonyms:37706-08-4;diethyl (diethylamino)propanedioate;NSC158337;diethyl N,N-diethylaminomalonate;SCHEMBL10782325;DTXSID50303437;KPXMMPKVFUVJMD-UHFFFAOYSA-N;AKOS024333792;NSC-158337;DIETHYL 2-(DIETHYLAMINO)-MALONATE

Suppliers and Price of Diethyl (diethylamino)propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Diethyl (diethylamino)propanedioate

Chemical Property:

Vapor Pressure:0.0041mmHg at 25°C
Boiling Point:279.1°Cat760mmHg
Flash Point:122.6°C
Density:1.029g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:231.14705815
Heavy Atom Count:16
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(C(=O)OCC)C(=O)OCC

Technology Process of Diethyl (diethylamino)propanedioate

There total 5 articles about Diethyl (diethylamino)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 685-87-0
Diethyl 2-bromomalonate

: 109-89-7
diethylamine

: 37706-08-4
diethyl 2-(diethylamino)malonate

Guidance literature:: In ethanol; at 20 ℃; for 15h;

Reference yield: 53.0%

: 20893-05-4
diethyl 2-[(tosyloxy)imino]malonate

: 925-90-6
ethylmagnesium bromide

: 37706-08-4
diethyl 2-(diethylamino)malonate

Guidance literature:: In diethyl ether; toluene; at 30 ℃; for 0.25h; Inert atmosphere;
DOI:10.1016/j.tet.2015.04.111

Reference yield:

: 609-09-6
Diethyl ketomalonate

: 37706-08-4
diethyl 2-(diethylamino)malonate

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; pyridine / 24 h / Inert atmosphere; Reflux

2: triethylamine / dichloromethane / 12 h / 0 °C

3: toluene; diethyl ether / 0.25 h / 30 °C / Inert atmosphere

With pyridine; hydroxylamine hydrochloride; triethylamine; In diethyl ether; dichloromethane; toluene;
DOI:10.1016/j.tet.2015.04.111