4-(Thiophen-2-YL)morpholine

Base Information

Chemical Name:4-(Thiophen-2-YL)morpholine
CAS No.:19983-19-8
Molecular Formula:C8H11 N O S
Molecular Weight:169.24
Hs Code.:
DSSTox Substance ID:DTXSID60568813
Nikkaji Number:J1.467.169B
Wikidata:Q82455186
Mol file:19983-19-8.mol

Synonyms:4-(THIOPHEN-2-YL)MORPHOLINE;19983-19-8;4-thiophen-2-ylmorpholine;2-MORPHOLINO-THIOPHENE;5-morpholinothiophene;SCHEMBL6345668;DTXSID60568813;MFCD00142950;AKOS022670559

Suppliers and Price of 4-(Thiophen-2-YL)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 4-(Thiophen-2-YL)morpholine

Chemical Property:

PSA：40.71000
LogP:1.64970
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:169.05613515
Heavy Atom Count:11
Complexity:125

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CC=CS2

Technology Process of 4-(Thiophen-2-YL)morpholine

There total 9 articles about 4-(Thiophen-2-YL)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 110-91-8,99108-56-2
morpholine

: 96-43-5
2-thienyl chloride

: 19983-19-8
4-(2-thiophenyl)morpholine

Guidance literature:: With potassium tert-butylate; C₆₆H₉₂Cl₃N₃Pd; In n-heptane; at 100 ℃; for 4h;
DOI:10.1002/chem.202103341

Reference yield: 89.0%

: 110-91-8,99108-56-2
morpholine

: 1003-09-4
2-bromothiophene

: 19983-19-8
4-(2-thiophenyl)morpholine

Guidance literature:: With potassium tert-butylate; In N,N-dimethyl-formamide; at 100 ℃; for 12h;
DOI:10.1002/aoc.3906

Reference yield: 86.0%

: 5765-65-1
4-(benzoyloxy)morpholine

: C₁₂H₂₃AlOS

: 19983-19-8
4-(2-thiophenyl)morpholine

Guidance literature:: 4-(benzoyloxy)morpholine; With copper(l) iodide; In tetrahydrofuran; at 20 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;

C₁₂H₂₃AlOS; In tetrahydrofuran; at 20 ℃; for 1h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.joc.5b00767