(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

Base Information

Chemical Name:(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester
CAS No.:1007598-26-6
Molecular Formula:C₃₂H₄₀F₂NO₅P
Molecular Weight:587.644
Hs Code.:

Synonyms:(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

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Chemical Property of (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

Chemical Property:

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Technology Process of (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

There total 1 articles about (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62918-50-7
4-(4-octoxyphenyl)benzoyl chloride

: 503856-36-8
diethyl [difluoro(2-aminophenyl)methyl]phosphonate

: 1007598-26-6
(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 0.166667 - 0.333333h;

Reference yield:

: 1007598-26-6
(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

: (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid monoethyl ester

Guidance literature:: (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 24h;

With hydrogenchloride; water; In tetrahydrofuran; ethyl acetate;

Reference yield:

: 1007598-26-6
(difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

: 74-88-4
methyl iodide

: (difluoro-{2-[methyl-(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid ethyl ester methyl ester

: (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid ethyl ester methyl ester

: (difluoro-{2-[methyl-(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester

Guidance literature:: (difluoro-{2-[(4'-octyloxy-biphenyl-4-carbonyl)-amino]-phenyl}-methyl)-phosphonic acid diethyl ester; methyl iodide; With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 3h;

With diazomethane; In tetrahydrofuran; diethyl ether; ethyl acetate;