tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Base Information

Chemical Name:tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride
CAS No.:335620-99-0
Molecular Formula:C₁₈H₂₆N₂O₃*ClH
Molecular Weight:354.877
Hs Code.:

Synonyms:335620-99-0;tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride;9-Oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylic acid, 7-(phenylmethyl)-, 1,1-dimethylethyl ester, hydrochloride (1:1);SCHEMBL2966195;WAIBGYDSVMGVJD-UHFFFAOYSA-N;tert-butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate;hydrochloride

Suppliers and Price of tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:354.1710204
Heavy Atom Count:24
Complexity:401

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC2CN(CC(C1)O2)CC3=CC=CC=C3.Cl

Technology Process of tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

There total 5 articles about tert-Butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 335620-98-9
tert-butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate

: 335620-99-0
tert-butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; ethyl acetate; at -10 ℃; for 1h; Inert atmosphere;

Reference yield:

: 30569-34-7
N,N-bis(oxiran-2-ylmethyl)benzenesulfonamide

: 335620-99-0
tert-butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1.1: ethanol / 3 h / 80 °C

2.1: methanesulfonic acid / toluene / 16 h / 110 °C

3.1: hydrogen bromide / water / 32 h / 105 °C

3.2: 1 h

4.1: sodium hydrogencarbonate / water; dichloromethane / 1.5 h / 20 °C

5.1: hydrogenchloride / ethyl acetate; diethyl ether / 1 h / -10 °C / Inert atmosphere

With hydrogenchloride; methanesulfonic acid; hydrogen bromide; sodium hydrogencarbonate; In diethyl ether; ethanol; dichloromethane; water; ethyl acetate; toluene;

Reference yield:

: 335621-26-6
1-benzyl-5-(phenylsulfonyl)-1,5-diazoctane-3,7-diol

: 335620-99-0
tert-butyl 7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: methanesulfonic acid / toluene / 16 h / 110 °C

2.1: hydrogen bromide / water / 32 h / 105 °C

2.2: 1 h

3.1: sodium hydrogencarbonate / water; dichloromethane / 1.5 h / 20 °C

4.1: hydrogenchloride / ethyl acetate; diethyl ether / 1 h / -10 °C / Inert atmosphere

With hydrogenchloride; methanesulfonic acid; hydrogen bromide; sodium hydrogencarbonate; In diethyl ether; dichloromethane; water; ethyl acetate; toluene;