Technology Process of 2-methylene-19,21-dinor-1α-hydroxybishomopregnacalciferol
There total 11 articles about 2-methylene-19,21-dinor-1α-hydroxybishomopregnacalciferol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: sodium periodate / ruthenium trichloride
2: n-butyllithium
3: lithium aluminium tetrahydride
4: sodium periodate
5: lithium diisopropyl amide
6: diisobutylaluminium hydride
7: n-butyllithium; p-toluenesulfonyl chloride
9: tetrabutyl ammonium fluoride
With
sodium periodate; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; p-toluenesulfonyl chloride; lithium diisopropyl amide;
ruthenium trichloride;
7: Wittig-Horner coupling / 8: Wittig-Horner coupling;
- Guidance literature:
-
Multi-step reaction with 10 steps
2: sodium periodate / ruthenium trichloride
3: n-butyllithium
4: lithium aluminium tetrahydride
5: sodium periodate
6: lithium diisopropyl amide
7: diisobutylaluminium hydride
8: n-butyllithium; p-toluenesulfonyl chloride
10: tetrabutyl ammonium fluoride
With
sodium periodate; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; p-toluenesulfonyl chloride; lithium diisopropyl amide;
ruthenium trichloride;
8: Wittig-Horner coupling / 9: Wittig-Horner coupling;
