[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Base Information

Chemical Name:[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide
CAS No.:213250-64-7
Molecular Formula:C₃₃H₅₁O₃PSi₂
Molecular Weight:582.911
Hs Code.:

Synonyms:[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Suppliers and Price of [2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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TRC
(2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)-4-methylenecyclohexylidene)ethyl)diphenylphosphineOxide
25mg
$ 495.00

Total 3 raw suppliers

Chemical Property of [2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Chemical Property:

Purity/Quality:: (2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)-4-methylenecyclohexylidene)ethyl)diphenylphosphineOxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)-4-methylenecyclohexylidene)ethyl)diphenylphosphine Oxide is an intermediate used in the preparation of vitamin D3 analogs

Technology Process of [2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

There total 22 articles about [2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 829-85-6
diphenylphosphane

: 213250-63-6
2-((3R,5R)-3,5-bis(tertbutyldimethylsilyloxy)-4-methylenecyclohexylidene)ethanol

: 213250-64-7
[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Guidance literature:: 2-((3R,5R)-3,5-bis(tertbutyldimethylsilyloxy)-4-methylenecyclohexylidene)ethanol; With n-butyllithium; p-toluenesulfonyl chloride; In tetrahydrofuran; hexanes; at 0 ℃; for 0.0833333h;

diphenylphosphane; With n-butyllithium; In tetrahydrofuran; hexanes; at 0 ℃; for 0.5h;

With dihydrogen peroxide; In dichloromethane; water; at 0 ℃; for 1h;

Reference yield: 87.0%

: 829-85-6
diphenylphosphane

: Toluene-4-sulfonic acid 2-[(3R,5R)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-4-methylene-cyclohexylidene]-ethyl ester

: 213250-64-7
[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Guidance literature:: diphenylphosphane; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃;

Toluene-4-sulfonic acid 2-[(3R,5R)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-4-methylene-cyclohexylidene]-ethyl ester; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h;

With water; dihydrogen peroxide; more than 3 stages;

Reference yield: 87.0%

: 98-59-9
p-toluenesulfonyl chloride

: 829-85-6
diphenylphosphane

: 213250-63-6
2-((3R,5R)-3,5-bis(tertbutyldimethylsilyloxy)-4-methylenecyclohexylidene)ethanol

: 213250-64-7
[2-[(3'R,5'R)-3',5'-bis[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

Guidance literature:: p-toluenesulfonyl chloride; 2-((3R,5R)-3,5-bis(tertbutyldimethylsilyloxy)-4-methylenecyclohexylidene)ethanol; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.0833333h;

diphenylphosphane; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 1h;

With dihydrogen peroxide; In dichloromethane; at 0 ℃; for 1h;