1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate

Base Information

Chemical Name:1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate
CAS No.:630121-00-5
Molecular Formula:C₂₂H₂₆N₂O₃
Molecular Weight:366.46
Hs Code.:
DSSTox Substance ID:DTXSID001126318

Synonyms:SCHEMBL4006887;DTXSID001126318;630121-00-5

Suppliers and Price of 1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:366.19434270
Heavy Atom Count:27
Complexity:520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(=CC1)C2=NC=C(C=C2)OCC3=CC=CC=C3

Technology Process of 1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate

There total 2 articles about 1,1-Dimethylethyl 3',6'-dihydro-5-(phenylmethoxy)[2,4'-bipyridine]-1'(2'H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 138647-49-1
4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

: 630121-00-5
tert-butyl 5-(benzyloxy)-3',6'-dihydro-2,4'-bipyridine-1'(2'H)-carboxylate

Guidance literature:: 5-(benzyloxy)-2-bromopyridine; With n-butyllithium; In diethyl ether; at -78 ℃; for 0.166667h;

With zinc(II) chloride; In diethyl ether; at 0 ℃; for 0.25h;

4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 60 ℃; for 4h;