4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

Base Information

Chemical Name:4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide
CAS No.:1008764-10-0
Molecular Formula:C₂₆H₃₃N₃O₅
Molecular Weight:467.565
Hs Code.:

Synonyms:4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

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Chemical Property of 4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

Chemical Property:

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Technology Process of 4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

There total 4 articles about 4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1008775-29-8
5-[({4-[3-(2-cyclohexylethoxy)benzoyl]piperazin-1-yl}carbonyl)amino]-1,3-phenylene diacetate

: 1008764-10-0
4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

Guidance literature:: 5-[({4-[3-(2-cyclohexylethoxy)benzoyl]piperazin-1-yl}carbonyl)amino]-1,3-phenylene diacetate; With sodium hydroxide; water; isopropyl alcohol; for 3h;

With hydrogenchloride; water; In isopropyl alcohol;

Reference yield:

: C₁₁H₉NO₅

: 1008764-10-0
4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / 2 h / 20 °C

2: sodium hydroxide; water; isopropyl alcohol / 3 h

With sodium hydroxide; water; triethylamine; isopropyl alcohol; In acetonitrile;

Reference yield:

: C₁₁H₉N₃O₅

: 1008764-10-0
4-[3-(2-cyclohexylethoxy)benzoyl]-N-(3,5-dihydroxyphenyl)piperazine-1-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 4 h / 100 °C

2: triethylamine / acetonitrile / 2 h / 20 °C

3: sodium hydroxide; water; isopropyl alcohol / 3 h

With sodium hydroxide; water; triethylamine; isopropyl alcohol; In toluene; acetonitrile;