2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Base Information

Chemical Name:2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid
CAS No.:403736-43-6
Molecular Formula:C₁₅H₁₆N₄O₅S
Molecular Weight:364.382
Hs Code.:

2-benzyloxycarbonylamino-<i>N</i>-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Synonyms:2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Suppliers and Price of 2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

There total 1 articles about 2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 17467-35-5
3-methyl-1,2,4-thiadiazol-5-amine

: 4515-23-5
N-benzyloxycarbonyl-L-aspartic acid anhydride

: 403736-43-6
2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

Guidance literature:: In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1016/S0968-0896(01)00228-0

Reference yield: 95.0%

: 27532-96-3
glycine tert-butyl ester hydrochloride

: 403736-43-6
2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

: [2-benzyloxycarbonylamino-3-(3-methyl-[1,2,4]thiadiazol-5-ylcarbamoyl)-propionylamino]-acetic acid tert-butyl ester

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1016/S0968-0896(01)00228-0

Reference yield:

: 403736-43-6
2-benzyloxycarbonylamino-N-(3-methyl-[1,2,4]thiadiazol-5-yl)-succinamic acid

: [(S)-2-Benzyloxycarbonylamino-3-(3-methyl-[1,2,4]thiadiazol-5-ylcarbamoyl)-propionylamino]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / EDC hydrochloride; triethylamine / CH₂Cl₂ / 12 h / 20 °C

2: 100 percent / HCl / CH₂Cl₂ / 4 h / 20 °C

With hydrogenchloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;
DOI:10.1016/S0968-0896(01)00228-0