2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

Base Information

Chemical Name:2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol
CAS No.:1616294-98-4
Molecular Formula:C₂₆H₃₃N₅O₃
Molecular Weight:463.58
Hs Code.:

Synonyms:2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

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Chemical Property of 2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

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Technology Process of 2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

There total 2 articles about 2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 1616296-00-4
C₂₂H₂₅N₅O

: 540-51-2
2-bromoethanol

: 1616294-98-4
2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

: 1616296-04-8
C₂₄H₂₉N₅O₂

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃;

Reference yield:

: 1616295-99-8
C₂₂H₂₃N₅O₃

: 1616294-98-4
2,2'-((2-cyclopropyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazolin-6-yl)azanediyl)diethanol

Guidance literature:: Multi-step reaction with 2 steps

1: iron; ammonium chloride / ethanol; water / 3 h / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 120 °C

With iron; potassium carbonate; ammonium chloride; In ethanol; water; N,N-dimethyl-formamide;