N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate

Base Information

• Chemical Name: N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate
• CAS No.: 1460308-45-5
• Molecular Formula: C₁₈H₁₇INO₄S*F₆P
• Molecular Weight: 615.272
• Mol file: 1460308-45-5.mol

Synonyms:N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate

Chemical Property of N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate

There total 3 articles about N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.7%

N-(4-iodophenyl)pyridinium hexafluorophosphate (1460308-43-3) + toluene-4-sulfonic acid (104-15-4) → N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate (1460308-45-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1246/cl.130229

Reference yield:

pyridine (110-86-1) → N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate (1460308-45-5)

Guidance literature:

Multi-step reaction with 4 steps

1: acetone / 15 h / Reflux

2: 20 h / Reflux; Inert atmosphere

3: potassium hexafluorophosphate / water / 0.5 h / 20 °C

4: 3-chloro-benzenecarboperoxoic acid / acetonitrile / 20 °C / Inert atmosphere

With potassium hexafluorophosphate; 3-chloro-benzenecarboperoxoic acid; In water; acetone; acetonitrile;

DOI:10.1246/cl.130229

Reference yield:

1-(2,4-dinitrophenyl)-pyridinium chloride (4185-69-7) → N-{4-[hydroxyl(tosyloxy)iodophenyl]}pyridinium hexafluorophosphate (1460308-45-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 20 h / Reflux; Inert atmosphere

2: potassium hexafluorophosphate / water / 0.5 h / 20 °C

3: 3-chloro-benzenecarboperoxoic acid / acetonitrile / 20 °C / Inert atmosphere

With potassium hexafluorophosphate; 3-chloro-benzenecarboperoxoic acid; In water; acetonitrile;

DOI:10.1246/cl.130229

upstream raw materials:

pyridine

N-(4-iodophenyl)pyridinium hexafluorophosphate

toluene-4-sulfonic acid

1-(2,4-dinitrophenyl)-pyridinium chloride

Downstream raw materials:

2-hydroxy-5-(4-methylphenyl)sulfonyloxybenzaldehyde

2-acetyl-4-tosyloxyphenol

methyl 2-hydroxy-5-(p-tolylsulphonyloxy)benzoate