2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

Base Information

Chemical Name:2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate
CAS No.:1239583-12-0
Molecular Formula:C₅₄H₅₆N₅O₁₅P
Molecular Weight:1046.04
Hs Code.:

Synonyms:2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

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Chemical Property of 2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

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Technology Process of 2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

There total 1 articles about 2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₅₄H₅₆N₅O₁₄P

: 1239583-12-0
2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetonitrile; at 0 ℃; Inert atmosphere;
DOI:10.1021/jo100757t

Reference yield: 56.0%

: 1239583-12-0
2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl allyl ester)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

: 1239583-15-3
2-cyanoethoxy(Nα-Fmoc-tyrosin-4-yl)(4-N-benzoyl-2',3'-di-O-isobutyrylcytidinyl-5'-yl)phosphate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-n-butyl-tin hydride; acetic acid; In tetrahydrofuran; dichloromethane; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jo100757t