6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE

Base Information

Chemical Name:6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE
CAS No.:19369-30-3
Molecular Formula:C11H10 F N3 O2
Molecular Weight:235.2144032
Hs Code.:2933599090
Mol file:19369-30-3.mol

Synonyms:Uracil,6-amino-1-(p-fluorophenyl)-3-methyl- (8CI);6-Amino-1-(4-fluorophenyl)-3-methyluracil

Suppliers and Price of 6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE 95.00%
5MG
$ 501.84

Total 3 raw suppliers

Chemical Property of 6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE

Chemical Property:

PSA：70.02000
LogP:0.83870

Purity/Quality:

99% ^*data from raw suppliers

6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE

There total 2 articles about 6-AMINO-1-(4-FLUORO-PHENYL)-3-METHYL-1H-PYRIMIDINE-2,4-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 772-55-4
N-(4-fluorophenyl)-N'-methyl-urea

: 19369-30-3
6-amino-1-(4-fluoro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: Ac₂O / acetic acid / 80 °C

2: 2N NaOH

With sodium hydroxide; acetic anhydride; In acetic acid; 1: Acylation / 2: Cyclization;
DOI:10.1016/S0968-0896(00)00126-7

Reference yield:

: 301206-16-6
1-(2-Cyano-acetyl)-3-(4-fluoro-phenyl)-1-methyl-urea

: 19369-30-3
6-amino-1-(4-fluoro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: With sodium hydroxide;
DOI:10.1016/S0968-0896(00)00126-7

Reference yield:

: 19369-30-3
6-amino-1-(4-fluoro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

: 19677-96-4
5,6-diamino-1-(4-fluoro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: 6-amino-1-(4-fluoro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione; With hydrogenchloride; sodium nitrite;

With hydrogen; palladium on activated charcoal; In ethanol; Heating;
DOI:10.1016/S0968-0896(00)00126-7