6-chloro-3,4-dihydro-1H-quinolin-2-one

Base Information

Chemical Name:6-chloro-3,4-dihydro-1H-quinolin-2-one
CAS No.:19358-40-8
Molecular Formula:C9H8 Cl N O
Molecular Weight:181.622
Hs Code.:2933499090
European Community (EC) Number:800-177-1
DSSTox Substance ID:DTXSID20459758
Nikkaji Number:J1.357.219D
Wikidata:Q82283601
Mol file:19358-40-8.mol

Synonyms:19358-40-8;6-chloro-3,4-dihydro-1H-quinolin-2-one;6-chloro-3,4-dihydroquinolin-2(1H)-one;6-chloro-1,2,3,4-tetrahydroquinolin-2-one;SCHEMBL1764573;DTXSID20459758;QKDOVTGWTBEYMG-UHFFFAOYSA-N;MFCD09833202;AKOS015999671;AKOS022140448;BH-0717;CS-0155444;EN300-49419;Z586255942

Suppliers and Price of 6-chloro-3,4-dihydro-1H-quinolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one
50mg
$ 60.00

Matrix Scientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one >97%
1g
$ 166.00

Matrix Scientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one >97%
500mg
$ 133.00

Matrix Scientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one >97%
5g
$ 387.00

Crysdot
6-Chloro-3,4-dihydroquinolin-2(1H)-one 95+%
10g
$ 452.00

Chemenu
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one 95%
10g
$ 427.00

Apolloscientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one
5g
$ 269.00

Apolloscientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one
1g
$ 116.00

Apolloscientific
6-Chloro-1,2,3,4-tetrahydroquinolin-2-one
500mg
$ 93.00

American Custom Chemicals Corporation
6-CHLORO-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE 95.00%
1G
$ 721.57

Total 23 raw suppliers

Chemical Property of 6-chloro-3,4-dihydro-1H-quinolin-2-one

Chemical Property:

Melting Point:106 °C
Boiling Point:362.5±42.0 °C(Predicted)
PKA:13.86±0.20(Predicted)
PSA：29.10000
Density:1.290±0.06 g/cm3(Predicted)
LogP:2.36270
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:181.0294416
Heavy Atom Count:12
Complexity:195

Purity/Quality:

99.0% ^*data from raw suppliers

6-Chloro-1,2,3,4-tetrahydroquinolin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC2=C1C=C(C=C2)Cl

Technology Process of 6-chloro-3,4-dihydro-1H-quinolin-2-one

There total 20 articles about 6-chloro-3,4-dihydro-1H-quinolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 457622-18-3
3-(2-amino-5-chlorophenyl)-1-propanol

: 19358-40-8
6-chloro-1,2,3,4-tetrahydroquinolin-2-one

Guidance literature:: With potassium carbonate; [pentamethylcyclopentadienylRhCl₂]2; In acetone; at 100 ℃; for 20h;
DOI:10.1021/ol0489954

Reference yield: 94.0%

: 19314-16-0
3-chloro-N-(4-chlorophenyl)propanamide

: 19358-40-8
6-chloro-1,2,3,4-tetrahydroquinolin-2-one

Guidance literature:: With aluminium trichloride; at 140 ℃; for 24h;
DOI:10.1021/jm000945r

Reference yield: 94.0%

: 3-(4-chlorophenethyl)-1,4,2-dioxazol-5-one

: 19358-40-8
6-chloro-1,2,3,4-tetrahydroquinolin-2-one

Guidance literature:: With C₁₉H₁₉Cl₃IrNO; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; at 60 ℃; for 12h; regioselective reaction; Sealed tube;
DOI:10.1002/anie.201808892