4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

Base Information

Chemical Name:4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester
CAS No.:952795-35-6
Molecular Formula:C₂₀H₁₉F₆NO₂
Molecular Weight:419.367
Hs Code.:

Synonyms:4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

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Chemical Property of 4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

Chemical Property:

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Technology Process of 4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

There total 4 articles about 4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 952714-26-0
benzyl (2S)-4,4,4-trifluoro-2-{[(1R)-1-phenylethyl]amino}-3-(trifluoromethyl)butanoate hydrochloride

: 952795-35-6
4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

Guidance literature:: With sodium hydroxide; In water; toluene; pH=7;

Reference yield:

: 1763-28-6
(4,4,4)-trifluoro-3-(trifluoromethyl)but-2-enoic acid

: 952795-35-6
4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / PCl₅, Et₃N

2: methanol / 1 h / Ambient temperature

With phosphorus pentachloride; triethylamine; In methanol;
DOI:10.1002/hlca.19980810117

Reference yield:

: 100-51-6,185532-71-2
benzyl alcohol

: 952795-35-6
4,4,4,4',4',4'-hexafluoro-N-[(1R)-1-phenylethyl]-L-valine phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / PCl₅, Et₃N

2: methanol / 1 h / Ambient temperature

With phosphorus pentachloride; triethylamine; In methanol;
DOI:10.1002/hlca.19980810117