(Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

Base Information

Chemical Name:(Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine
CAS No.:1591705-17-7
Molecular Formula:C₁₂H₁₅Cl₂NOS
Molecular Weight:292.229
Hs Code.:

Synonyms:(Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

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Technology Process of (Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

There total 2 articles about (Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5926-38-5
(dichloromethyl)trimethylsilane

: 507469-89-8
(R)-(-)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide

: 1591705-17-7
(Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at -20 ℃; for 0.5h;

Reference yield: 51.0%

: 5926-38-5
(dichloromethyl)trimethylsilane

: 507469-89-8
(R)-(-)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide

: 1591705-17-7
(Rs,2R,3S)-1-(tert-butylsulfinyl)-2-chloro-3-(4-chlorophenyl)aziridine

: C₁₂H₁₅Cl₂NOS

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -70 - 20 ℃; for 1.5h; diastereoselective reaction;
DOI:10.1039/c4ra00471j