Z-GLY-D-ALA-OH

Base Information

• Chemical Name: Z-GLY-D-ALA-OH
• CAS No.: 19245-97-7
• Molecular Formula: C₁₃H₁₆N₂O₅
• Molecular Weight: 280.28
• Mol file: 19245-97-7.mol

Synonyms:Alanine,N-(N-carboxyglycyl)-, N-benzyl ester, D- (8CI); D-Alanine,N-[N-[(phenylmethoxy)carbonyl]glycyl]-; N-Benzyloxycarbonylglycyl-D-alanine

Chemical Property of Z-GLY-D-ALA-OH

Chemical Property:

• PSA: 104.73000
• LogP: 1.28390

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-GLY-D-ALA-OH

There total 6 articles about Z-GLY-D-ALA-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-Gly-D-Ala-OEt (64532-71-4) → Cbz-Gly-D-Ala-OH (19245-97-7)

Guidance literature:

With sodium hydroxide; acetone;

DOI:10.1021/ja01151a512

Reference yield:

(R)-tert-butyl 2-(2-(((benzyloxy)carbonyl)amino)acetamido)propanoate → Cbz-Gly-D-Ala-OH (19245-97-7)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1021/ja00460a039

Reference yield:

N-(benzyloxycarbonyl)glycine hydrazide (5680-83-1) → Cbz-Gly-D-Ala-OH (19245-97-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₂; aqueous acetic acid; aqueous HCl / Behandeln einer Loesung des Reaktionsprodukts in Aether mit D-Alanin-aethylester

2: aqueous NaOH; acetone

With hydrogenchloride; sodium hydroxide; acetic acid; acetone; sodium nitrite;

DOI:10.1021/ja01151a512

upstream raw materials:

Z-Gly-D-Ala-OEt

D-Alanine

N-(Benzyloxycarbonyl)glycine

N-(benzyloxycarbonyl)glycine hydrazide

Downstream raw materials:

(S)-2-({(R)-1-[(R)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-2-phenyl-ethyl}-methoxy-phosphinoyloxy)-3-phenyl-propionic acid 3-pyridin-4-yl-propyl ester